Bill & Melinda Gates Foundation
Private · Global / National
Invite-onlyWorld's largest private foundation. Funds K-12 education reform, global health (vaccines, maternal health), and US economic mobility. Mostly invite-only; open RFPs published periodically.
- Assets
- $75.2B
- Avg grant
- $100K–$10M
global healtheducationequityclimate
Visit funder →Robert Wood Johnson Foundation
Private · National
RFP / LOI cyclesLargest US philanthropy focused on health. Funds health-equity research, community health interventions, public-health policy. Publishes recurring RFPs.
- Assets
- $13.6B
- Avg grant
- $50K–$2M
healthequityresearch
Visit funder →Ford Foundation
Private · National / Global
Invite-onlyFunds social justice, inequality reduction, civic engagement, free expression, and creative arts. Mostly invite; LOIs accepted in some programs.
- Assets
- $16B
- Avg grant
- $100K–$1M
equityartscivichuman rights
Visit funder →John D. and Catherine T. MacArthur Foundation
Private · National
Invite-onlyBig-bet philanthropy on climate solutions, criminal justice reform, nuclear security, and local Chicago programs. Invite + 100&Change open challenge.
- Assets
- $8.2B
- Avg grant
- $100K–$5M
climatecriminal justicejournalismtech & society
Visit funder →Knight Foundation
Private · 26 US cities
RFP / LOI cyclesFunds informed and engaged communities — local journalism, arts, civic innovation. Open Knight Cities Challenge and Knight News Challenge series.
- Assets
- $2.6B
- Avg grant
- $25K–$500K
journalismartscivic techcommunities
Visit funder →William and Flora Hewlett Foundation
Private · National / Global
Invite-onlyFunds open educational resources, climate solutions, reproductive rights, cyber policy, and Bay Area performing arts. Invite-only.
- Assets
- $13.1B
- Avg grant
- $100K–$1M
educationenvironmentglobal developmentperforming arts
Visit funder →The Kresge Foundation
Private · National / Detroit
RFP / LOI cyclesExpands opportunities in American cities. Strong arts & culture, climate resilience, and place-based Detroit programs. Open RFPs by program.
- Assets
- $4.2B
- Avg grant
- $150K–$1M
artseducationenvironmenthealthhuman services
Visit funder →Charles Stewart Mott Foundation
Family · National / Global
RFP / LOI cyclesFunds civil society, afterschool learning, freshwater conservation, and place-based work in Flint, MI. Accepts LOIs year-round.
- Assets
- $3.5B
- Avg grant
- $50K–$500K
civil societyeducationenvironmentFlint
Visit funder →Google.org
Corporate · Global
RFP / LOI cyclesGoogle's philanthropic arm. Funds AI for social good, nonprofit tech adoption, crisis response, and STEM education. Open challenges and AI Impact Accelerator.
- Assets
- Corporate program
- Avg grant
- $250K–$25M
AI for goodtecheducationclimate
Visit funder →Microsoft Philanthropies
Corporate · Global
Open applicationProvides cash + Azure/Microsoft 365 credits to nonprofits. AI for Good, Skills for Jobs, Airband (rural broadband). Open application portal.
- Assets
- Corporate program
- Avg grant
- Software + cash
digital skillsAIbroadbandnonprofits
Visit funder →OpenAI Academy & Nonprofit Program
Corporate · Global
Open applicationDiscounted ChatGPT Team/Enterprise and API credits for 501(c)(3) nonprofits. Application-based, rolling.
- Assets
- Credits program
- Avg grant
- API credits + discounts
AI accesseducationnonprofits
Visit funder →Walton Family Foundation
Family · National / Regional
Invite-onlyK-12 charter & choice, oceans & freshwater, and Home Region (NW Arkansas, Delta). Mostly invite; some open initiatives.
- Assets
- $7.2B
- Avg grant
- $100K–$2M
educationenvironmentArkansas/Mississippi Delta
Visit funder →David and Lucile Packard Foundation
Family · National / Global
Invite-onlyChildren, families, communities; oceans & climate; population & reproductive health. Invite-only for most programs.
- Assets
- $8.2B
- Avg grant
- $100K–$1M
childrenoceansclimatereproductive health
Visit funder →Gordon and Betty Moore Foundation
Private · National
Invite-onlyBasic science research, environmental conservation, Bay Area patient-care quality. Invite-only with rare RFPs.
- Assets
- $8.4B
- Avg grant
- $500K–$5M
scienceenvironmentpatient care
Visit funder →Alfred P. Sloan Foundation
Private · National
RFP / LOI cyclesSTEM research, public understanding of science, economics. Open LOI process — Sloan Research Fellowships annually.
- Assets
- $2.0B
- Avg grant
- $50K–$500K
sciencetecheconomicsresearch
Visit funder →Simons Foundation
Private · National
RFP / LOI cyclesBasic math & physical sciences, autism research (SFARI), life sciences collaborations. Open RFPs and fellowships.
- Assets
- $5B+
- Avg grant
- $100K–$5M
mathphysicsautism researchlife sciences
Visit funder →Chan Zuckerberg Initiative
Operating · National
RFP / LOI cyclesFunds biomedical science (cell atlas, rare disease), personalized learning, US justice & opportunity. RFPs published quarterly.
- Assets
- LLC (no public assets)
- Avg grant
- $250K–$10M
scienceeducationjusticeAI
Visit funder →Arnold Ventures
Private · National
RFP / LOI cyclesEvidence-based policy reform. Funds rigorous research, pilots, and advocacy across criminal justice, health-care costs, and education. RFP-driven.
- Assets
- $2B+
- Avg grant
- $100K–$3M
criminal justicehealtheducationpublic finance
Visit funder →Social Science Research Council
Operating · National / Global
RFP / LOI cyclesFellowships and competitions for social science researchers across dozens of programs. Open applications.
- Assets
- Operating
- Avg grant
- $25K–$100K fellowships
researchfellowshipssocial science
Visit funder →New York Community Trust
Community · New York metro
RFP / LOI cyclesLargest community foundation serving NYC. Open LOIs across health, education, environment, arts, and human justice.
- Assets
- $3.5B
- Avg grant
- $25K–$250K
NYC nonprofitseducationhealtharts
Visit funder →The San Francisco Foundation
Community · Bay Area
RFP / LOI cyclesBay Area-focused community foundation. People, place, and power frame. Cycle-based open grants.
- Assets
- $1.6B
- Avg grant
- $25K–$200K
Bay Area equityhousingartseconomic security
Visit funder →CDC Foundation
Operating · National
RFP / LOI cyclesBridges public-health research with private funding. Partners on disease prevention, health equity, and emergency response.
- Assets
- Operating
- Avg grant
- $50K–$2M
public healthresearchemergencies
Visit funder →Amazon Future Engineer
Corporate · US / UK / Canada
Open applicationComputer science education program. Funds Title I schools, scholarships, and Code.org partnerships. Open application.
- Assets
- Corporate program
- Avg grant
- $10K–$100K + scholarships
CS educationK-12scholarships
Visit funder →Salesforce Foundation
Corporate · Global
Open application1-1-1 model — product, equity, and time. Nonprofits get Salesforce CRM + grants for tech-enabled service delivery.
- Assets
- Corporate 1-1-1
- Avg grant
- Product + cash
educationworkforcetech nonprofits
Visit funder →Patagonia Foundation
Corporate · Global
Open applicationGrassroots environmental activism — small, focused grants for groups protecting land, water, biodiversity, climate.
- Assets
- Corporate program
- Avg grant
- $5K–$25K
environmentgrassroots activism
Visit funder →